Luigi Manfre' , past Chairperson for Spine Committee and member of the Executive Committee of the   European   Society of Neuroradiology-ESNR (2017-2023), is the Secretary General of the European Society of Neuroradiology ESNR   (2023).  

He is part of the  European Board of Neuroradiology EBNR for the European School of Neuroradiology ESONR (2017), inaugural Member of the Interventional Spine Council of the American Society of Neuroradiology (ASNR, 2019), and Member of the Scientific Editorial Board of the European Radiology Journal, official journal of the European Society of Radiology ESR (2021). He is paper Reviewer of “Neuroradiology” journal,  “Interventional Neuroradiology Journal INJ” and “Journal of Vascular and Interventional Radiology JVIR”. He is a Scientific Member of the ASSR Research and Education Committee (2023-2024).

He was born in Catania, in 1965, on March the 31st. He attended the Classic High School diploma during the 1983 at the "M. Cutelli" Lyceum, in Catania, graded with the highest score. He got Medical Degree in 1989 and Specialization in Diagnostic and Interventional Radiology in 1993, working as a Researcher from 1993 to 2001 at Palermo University, and as an Interventional Neuroradiologist from 2001 at "Cannizzaro Hpt", in Catania, Italy. From the 2011 to 2016 directed the Haed of Minimal Invasive Spine Therapy Unit, at the "Cannizzaro Hpt" , Catania, Italy.  He is professor in charge at the Institute of Radiology of the University of Palermo and at the University of Verona. He is the Director of the Minimal Invasive Spine Therapy department at the Instituto of Oncology in Mediterranean (IOM).

His main interest is in percutaneous minimal invasive spine surgery using X-ray & CT-guided techniques, a field in which he personally perfomed more than 5000 procedures from 1999, mainly in local anesthesia only, including 3rd generation interspinous spacers, all augmentation procedures for the spine (Vertebro/Kypho/Vesselplasty/Vertebral stent), posterior interspinous spacers, posterior interbody fusion, radioablation, percutaneous discectomy and coblation, pain radicular block, transarticolar and intraarticular fixation, sacroiliac joint fusion, radio- and cryoablation of vertebral tumors.

He was one of the Founding Member of the European Vertebroplasty Research Team (EVEREST) in 2004.

He has teached Neuroradiology to medical students at the Medicine Faculty of Palermo, Dentistry Faculty of Palermo University, Radiology, and Neuroradiology at the Medicine Faculty of Catania University.

He teaches from June 2015 as Invited Professor at the Radiology Institute of the University of Palermo and from January 2022 at the Neuroscience Department of the University of Verona.

He has been a Boarding Member of the Haed & Neck section of Italian Society of Radiology (2000-2004). He has been a Boarding  Member of the Italian Association of Neuroradiology (2004-2006).

He is a member of the 2023-2024 ASSR Research and Education Committee.

He won 16 international and national prizes.

He won for three times the "best paper of the year" prize at the American Society of Spine Radiology (ASSR) in 2007, 2009, 2012.

He has been invited speakers in 296 international and national congresses, attending 373 national and international congresses and courses.

In particular, he was invited for a lecture at the following international meetings:

• American Society of Spinal Radiology Meeting-ASSR (2003, 2004, 2007, 2008, 2009, 2012, 2013, 2014, 2015, 2016, 2017, 2018, 2019, 2020, 2021)
• American Society of Neuroradiology-ASNR (2004, 2007, 2018)
• World Federation of Interventional and Therapeutic Neuroradiology-WFITN (2004, 2013, 2015, 2017, 2019)
• Joint Society of American & European Spine Radiology ASSR-ESNR (2009, 2011)
• European Course of Neuroradiology (1998, 2008, 2015, 2016, 2017,  2018).
• Advanced Course of HQ European Course in Spine Intervention (2009, 2011, 2017).
• Groupe de recherche interdisciplinaire sur les biomaterriaux osteo-articulaires injectable GRIBOI (2010, 2013, 2017).
• American Society of Spinal Radiology (ASSR) end European Society of Neuroradiology (ESNR)  joint neeting (2013)
• World Federation of Neuroradiological Societies (WFNRS) (2014).
• Advanced Course of HQ in Spine Neuroradiology, diagnostic and interventional (2016, 2017, 2018).
• Congress of the European Society of Neuroradiology – ESNR (2016, 2017, 2018, 2019, 2020).
• 31^st Annual Meeting of the North American Spine Society-NASS (2016)
• 2^nd Qatar Neuroscience Conference (2018)
• XIV Congresso Nacional Sociedade Portuguesa de Neurorradiologia (2018)
• European Congress of Radiology ECR (2019)
• 46° Congres Annuel de la Societè Francaise de Neuroradiologie SFNR  (2019)
• European Course in Neuroradiology: Tumors. 15th Cicle, Module 2 (2019).
• Society of Neurointerventional Surgery SNIS (2019).
• ESNR/ESSR European Course in Spine Radiology, 1st Cycle, 1st Module, Rome, 22-25 January 2020, con le relazioni dal titolo “Vertebroplasty in Tumors” and “Percutaneous treatment of Lumbar spinal canal and foramina stenosis”, Rome, 22-25 Gennaio 2020.
• 23rd ASSR Annual meeting, con la relazione dal titolo “The Future of Spine Interventions: the European Perspective”, Dana Point (California) 12-16 Febbraio 2020.
• 24th Annual meeting of the American Society of Spine Radiology ASSR, February 19-21, 2021, con la relazione dal titolo: “Vertebral augmentation and advances spinal procedures”.
• ESNR/ESSR European Course in Spine Radiology, 1st Cycle, 2nd Module, virtual, 20-23 marzo 2021, con le relazioni dal titolo “Vertebroplasty in Tumors” and “Percutaneous treatment of Lumbar spinal canal and foramina stenosis: “The Sacroiliac Joint Disease: What We as Spinal Interventional Neuro-/Rad can do today”, “Sacroplasty”, “Live Session: CT-guided spine treatments”.
• 44th ESNR Annual Meeting, con la relazione dal titolo “Advances in SPine Interventions”.
• 25th Annual meeting of the America Society of Spine Radiology ASSR 2022, con le relazioni dal titolo “Spacers” e “Weight bearing MR imaging, spacers and MR-guided procedures”, 23-27 febbraio 2022.
• XXII Symposium Neuroradiologicum , con la relazione dal titolo “The Evolution of percutaneous spacers”. New York 14-16 may 2022.

He is the Editor of the book series “New procedures in spinal interventional neuroradiology” (Springer 2015,2016,2017, 2021). He was one of the Authors of "Spine Imaging" (Educational Symposia, USA) in 2003, 2004, 2013, 2014 as well as "Spine Radiology" (Springer, 2007), "Minimally Invasive Therapy of Spine and Nerves" (Springer 2011), Interventional Neuroradiology of the Spine (Springer 2013), Imaging Spine after treatment (Springer 2013).

He published 244 papers, 67 cited on Medline ® and was one of the Author of the CD-ROM titled “Imaging of the upper cranial nerves”, sponsored by the European Society of Neuroradiology, Lasion Ed, Vol.I e II, Brugge, Belgium 1999, winning the “Magna Cum Laude” prize at the annual ASNR meeting in Atlanta, April 2000.

As Chair for Spine of the ESNR, he promoted the ESNR Spine Fellowship, starting from 2019, and created the ESNR Spine Full Hands-On Courses “Europe” & “Middle East”.

He organized the following scientific meetings: "Course on Neuroradiology" (Palermo, November  8-10 1994), “Seminars on Diagnostic and Interventional Neuroradiology”(Palermo, May 26-28 1997), “Advanced MRI”(Caltanissetta, June 19-20 1998), “1st  Italian Course on Spinal Interventional Neuroradiology” (Catania, 21-22 June 2002), "Italian Course of the Haed & Neck Radiological Society" (Catania 12-13 December 2003), “Minimal Invasive Spine Surgery” (Palermo, june 23-24, 2017).

He organized as Director the multidisciplinary international congress “Sicily Spine 2015”, Catania 29-31 october 2015.

He organized as Director the “8^th Advanced Course of HQ in Spine Neuroradiology, Diagnostic and Interventional”, Italy, Catania 28 june – 1 july 2017.

He organized as Director “9th Advanced Course of HQ in Spine Neuroradiology, Diagnostic and Interventional”, Malta, 8-10 november 2018.

He organized as Course Director the “ESNR Spine Full Hands-On Course “Europe”, Malta, 25-27 october 2019, and Catania 23-26 october 2021. He organized as Course Director the “ESNR Spine Full Hands-On Course “Middle East”, Doha (Qatar), 1-19 march 2022,

He organized as Course Director the first “ESNR/ESSR European Course in Spine Radiology, 1st Cycle, 1st Module”, Rome, 22-25 January 2020, and 2^nd module -virtual- 20-23 march 2021, and the 2cycle 1^st module, Porto 23-26 march 2022.

He was Invited Lecturer at the prestigious Queens Square Hospital, University College London Hospital NHS, London 2023, April 24-25.

He attended several department, as:

• Dept. Neuroradiology of Ancona General Hospital “Le Torrette”.
• Dept. Neuroradiology of  Ospedale Niguarda Ca’Grande di Milano.
• Pediatric Neuroradiological Department, Sick Children Hospital di Toronto, Canada.
• Dept. Neuroradiology of  Ospedale S. Maria della Misericordia di Udine.
• Department of Interventional Neuroradiology, University Hospital Strasburgo, Francia.
• Department of Interventional Neuroradiology, Pitié-Salpetriere Hopital, Parigi, Francia.
• Department of Interventional Neuroradiology, University of Leiden, Olanda.

From the 20th of June to the 16th of July 1994 he attended the department of Pediatric Neuroradiology at the Hospital for Sick Children in Toronto, directed by Prof. Derec Harwood-Nash.

He is a Full Member of:

• European Society of Neuroradiology (ESNR)
• Italian Association of Neuroradiology (AIN)
• Italian Association of Radiology (SIRM)
• European Society of Radiology (ESR)
• American Association of Spine Radiology (ASSR)
• World Federation of Interventional and Therapeutic Neuroradiology (WFITN)